Best hypoallergenic mattress protector

How we chose

We work from documents, not from using products; we have not tested any of these protectors ourselves. “Hypoallergenic” has no legal definition we could point to, so on this page a protector is called hypoallergenic only where the maker’s page uses the word, and then only as the maker’s claim. Where a page does not use the word, we report the material and any certification it states, and leave the label off. What “hypoallergenic” means covers the word at length.

The verdict for each product therefore has three parts: what the maker says, what the page says the product is made of, and which certifications the page names. We did not check any certification against its issuer’s directory. Dust mites are the reason many readers search for this product; our dust mite and bedding allergy explainer covers the cause. This page does not claim that any protector reduces mites or symptoms, because none of the facts we hold measures that.

What to look for

• The word and its basis. A maker that writes “hypoallergenic” should say what it rests on. Of the five pages, one uses the word and none ties it to a test we could see.
• Fabric. Cotton, polyester, and a polyester and viscose blend all appear here. Fibre is a material fact; it is not a promise about reactions.
• Waterproof layer. Four of the five use polyurethane in some form; one is not waterproof at all.
• Certification and its number. A number can be looked up; a statement without one cannot. We note which is which.
• Fit. Stated depth ranges vary by product and are listed below where the page gave them. Check them against your mattress.

For related bedding, see hypoallergenic mattress pads, toppers, pillow protectors and sheets; the wider overview is hypoallergenic bedding.

Avocado Green Mattress Organic Waterproof Mattress Protector

Per the maker’s page, read by our fetch on 2026-11-13, this protector has two layers of organic cotton around an ultra-thin, breathable polyurethane membrane (Susterra propanediol), with no fire retardants or antimicrobial treatments. The maker states: “GOTS Organic Certified by Control Union (CU863637).” The page also shows OEKO-TEX STANDARD 100 certificate no. 24.HUS.86422, and lists MADE SAFE and GREENGUARD Gold as on the page. We did not verify any of these against the issuers.

The captured page text does not use the word “hypoallergenic”, so we do not call this product hypoallergenic. It is the only product here whose page names a membrane made from a plant-derived propanediol, and the only one that says it has no added antimicrobial treatment. The maker page offers standard pocket (6 to 16 inches deep) and deep pocket (up to 22 inches) versions; our record does not state the size of the listing. The link goes to Amazon through an affiliate link.

Avocado Green Mattress Organic Waterproof Mattress Protector

Criteria status: Meets our criteria; the maker doesn’t call it hypoallergenic. Reason: the maker page names GOTS organic certification (CU863637) and OEKO-TEX STANDARD 100 certificate 24.HUS.86422, as the page states them. This is a statement about what the maker page shows under our published criteria, not a promise about any person’s reaction.

See also is Avocado hypoallergenic?.

Coop Home Goods Ultra-Tech Waterproof Mattress Protector

This product was captured from the maker’s page in a browser on 2026-11-13; our automated fetch was blocked, so we could not re-check it. The page describes Lulltra fabric (60% polyester, 40% bamboo-derived viscose rayon) with a soft, flexible 100% polyurethane waterproof backing, and states that it fits mattresses up to 15 inches deep. Six sizes, Twin to California King, are listed.

The maker states that every component is OEKO-TEX STANDARD 100 certified. No certificate number was shown on the page, so we cannot point you to a record. The page does not use the word “hypoallergenic” for this product. The page address refers to bamboo, but the fabric listed is a polyester and viscose blend, so read the fibre list rather than the name. The link goes to Amazon through an affiliate link. See is Coop Home Goods hypoallergenic?.

Coop Home Goods Ultra-Tech Waterproof Mattress Protector

Criteria status: Meets our criteria; the maker doesn’t call it hypoallergenic. Reason: the maker page states the fabric and backing materials and says every component is OEKO-TEX STANDARD 100 certified (certificate number not shown on the page). This is a statement about what the maker page shows under our published criteria, not a promise about any person’s reaction.

Parachute Cotton Mattress Protector

Captured from the maker’s page in a browser on 2026-11-13; our automated fetch was blocked, so this is a read we could not re-check. We captured King / Cal King only, and other sizes were not captured. The page states: “Made of 100% cotton (fabric and fill)”. It has a box-quilted top and a cotton cambric skirt with a continuous elastic hem, and fits mattresses up to 16 inches deep. The page shows OEKO-TEX STANDARD 100 21.HUS.61798 from Hohenstein HTTI; we did not check that certificate.

The page says “Not waterproof.” This is the difference that matters most: it is a quilted cotton layer, not a liquid barrier. The page text we captured does not use “hypoallergenic”. We found no Amazon listing; link goes to the maker’s site (not an affiliate link).

Parachute Cotton Mattress Protector

Criteria status: Meets our criteria; the maker doesn’t call it hypoallergenic. Reason: the maker page states 100% cotton fabric and fill and an OEKO-TEX STANDARD 100 certificate number as shown on the page. This is a statement about what the maker page shows under our published criteria, not a promise about any person’s reaction.

Purple Waterproof Mattress Protector

The maker page, read by our fetch on 2026-11-13, lists fabric as 100% polyester and a protective coating of 100% thermoplastic polyurethane. It states: “Silent, no-crinkle fabric is anti-microbial + hypoallergenic.” This is the only hypoallergenic wording among the five pages, and it is a maker claim. We found no certification for either “anti-microbial” or “hypoallergenic” on the page, so we cannot tell you what test, if any, stands behind them.

The page offers standard and deep pocket versions, Twin to Split King; it states no size for the listing we matched, so check it before ordering. The link goes to Amazon through an affiliate link. See is Purple hypoallergenic?.

Purple Waterproof Mattress Protector

Tempur-Pedic TEMPUR-Protect Mattress Protector

Per the maker’s page, read by our fetch on 2026-11-13, this is polyester fabric backed with a thin waterproof polyurethane laminate with added stretch, with the page naming ThermalSense fabric. The maker states: “Made of polyester fabric backed with a thin waterproof polyurethane laminate.” The Queen size is given as 60 by 80 inches, and the page says it fits mattresses 8 to 16 inches deep, with Twin to Split Cal King listed.

The page has no “hypoallergenic” wording and we found no certification on it, so the maker-stated material is the whole of what we can report. We found no Amazon listing; link goes to the maker’s site (not an affiliate link). See is Tempur-Pedic hypoallergenic?.

Tempur-Pedic TEMPUR-Protect Mattress Protector

Criteria status: Meets our criteria; the maker doesn’t call it hypoallergenic. Reason: the maker page states the polyester fabric and polyurethane laminate materials; it names no certification. This is a statement about what the maker page shows under our published criteria, not a promise about any person’s reaction.

What the label does not tell you

A material list and a certification name do not tell you whether a product will suit a particular sleeper, and none of this is advice on an allergy or skin condition; for that, ask a clinician or an allergy society. A certificate on a page is a statement that we did not confirm in the issuer’s database, and an organic claim, an anti-microbial claim and a hypoallergenic claim are three different things. If you are also choosing a mattress, pillow or covers to go with it, see the hypoallergenic mattress, pillows, comforter and duvet pages, and for the certification landscape see asthma and allergy friendly certification.